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Symbol Name ID |
Wnt5a
wingless-type MMTV integration site family, member 5A MGI:98958 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Clitoral hypoplasia |
Hypoplastic labia majora |
Micropenis |
Cryptorchidism |
| Disease(s) Associated with WNT5A | ||||
| autosomal dominant Robinow syndrome 1 |
| Mouse Phenotypes | reproductive system phenotype |
decreased primordial germ cell number |
increased primordial germ cell apoptosis |
abnormal primordial germ cell migration |
abnormal maternal decidual layer morphology |
abnormal reproductive system morphology |
absent external female genitalia |
abnormal uterus morphology |
absent external male genitalia |
genital tubercle hypoplasia |
abnormal embryo attachment |
abnormal uterine-embryonic axis |
impaired embryo implantation |
impaired spacing of implantation sites |
twin decidual capsule |
reduced female fertility |
decreased litter size |
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| Availability | Mouse Genotype | |||||||||||||||||
| Wnt5atm1Amc/Wnt5atm1Amc | ||||||||||||||||||
| Pgrtm2(cre)Lyd/Pgr+ Wnt5atm1.1Tpy/Wnt5atm1.1Tpy (conditional) |
* | |||||||||||||||||
| Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+ Pgrtm2(cre)Lyd/Pgr+ (conditional) |
* | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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